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pasmcs hmvecs  (PromoCell)


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    PromoCell pasmcs hmvecs
    Gremlin 1 expression in pulmonary arterial hypertension (PAH) clinical samples. A: Representative of high magnification images of colocalized expression of vWF and Grem1 in human pulmonary vessel endothelium. Arrows indicate positive staining. B: Lung sections from biopsies of controls and PAH patients were stained with an anti–Gremlin 1 antibody. Gremlin 1 staining in PAH patient is associated with plexiform lesions. Arrows indicate positive Gremlin 1 staining. C: Bone morphogenetic protein receptor type 2 (BMPR2) and Gremlin 1 mRNA analysis in primary microvascular endothelial cells (HMVEC) and pulmonary arterial smooth muscle cells <t>(PASMCs).</t> Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Data shown are representative from one donor of PASMCs and <t>HMVECs.</t> The experiments were performed in triplicate, with similar results observed in at least one other donor. D: Gremlin 1 mRNA expression in lungs from PAH patients. Secondary PAH lung samples were obtained from NDRI (n = 3). Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Original magnification, ×20 (A and B).
    Pasmcs Hmvecs, supplied by PromoCell, used in various techniques. Bioz Stars score: 95/100, based on 150 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pasmcs hmvecs/product/PromoCell
    Average 95 stars, based on 150 article reviews
    pasmcs hmvecs - by Bioz Stars, 2026-03
    95/100 stars

    Images

    1) Product Images from "Treatment with Anti–Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416–Induced Pulmonary Arterial Hypertension in Mice"

    Article Title: Treatment with Anti–Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416–Induced Pulmonary Arterial Hypertension in Mice

    Journal: The American Journal of Pathology

    doi: 10.1016/j.ajpath.2013.07.017

    Gremlin 1 expression in pulmonary arterial hypertension (PAH) clinical samples. A: Representative of high magnification images of colocalized expression of vWF and Grem1 in human pulmonary vessel endothelium. Arrows indicate positive staining. B: Lung sections from biopsies of controls and PAH patients were stained with an anti–Gremlin 1 antibody. Gremlin 1 staining in PAH patient is associated with plexiform lesions. Arrows indicate positive Gremlin 1 staining. C: Bone morphogenetic protein receptor type 2 (BMPR2) and Gremlin 1 mRNA analysis in primary microvascular endothelial cells (HMVEC) and pulmonary arterial smooth muscle cells (PASMCs). Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Data shown are representative from one donor of PASMCs and HMVECs. The experiments were performed in triplicate, with similar results observed in at least one other donor. D: Gremlin 1 mRNA expression in lungs from PAH patients. Secondary PAH lung samples were obtained from NDRI (n = 3). Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Original magnification, ×20 (A and B).
    Figure Legend Snippet: Gremlin 1 expression in pulmonary arterial hypertension (PAH) clinical samples. A: Representative of high magnification images of colocalized expression of vWF and Grem1 in human pulmonary vessel endothelium. Arrows indicate positive staining. B: Lung sections from biopsies of controls and PAH patients were stained with an anti–Gremlin 1 antibody. Gremlin 1 staining in PAH patient is associated with plexiform lesions. Arrows indicate positive Gremlin 1 staining. C: Bone morphogenetic protein receptor type 2 (BMPR2) and Gremlin 1 mRNA analysis in primary microvascular endothelial cells (HMVEC) and pulmonary arterial smooth muscle cells (PASMCs). Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Data shown are representative from one donor of PASMCs and HMVECs. The experiments were performed in triplicate, with similar results observed in at least one other donor. D: Gremlin 1 mRNA expression in lungs from PAH patients. Secondary PAH lung samples were obtained from NDRI (n = 3). Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Original magnification, ×20 (A and B).

    Techniques Used: Expressing, Staining, Reverse Transcription Polymerase Chain Reaction



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    pasmcs hmvecs  (PromoCell)
    95
    PromoCell pasmcs hmvecs
    Gremlin 1 expression in pulmonary arterial hypertension (PAH) clinical samples. A: Representative of high magnification images of colocalized expression of vWF and Grem1 in human pulmonary vessel endothelium. Arrows indicate positive staining. B: Lung sections from biopsies of controls and PAH patients were stained with an anti–Gremlin 1 antibody. Gremlin 1 staining in PAH patient is associated with plexiform lesions. Arrows indicate positive Gremlin 1 staining. C: Bone morphogenetic protein receptor type 2 (BMPR2) and Gremlin 1 mRNA analysis in primary microvascular endothelial cells (HMVEC) and pulmonary arterial smooth muscle cells <t>(PASMCs).</t> Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Data shown are representative from one donor of PASMCs and <t>HMVECs.</t> The experiments were performed in triplicate, with similar results observed in at least one other donor. D: Gremlin 1 mRNA expression in lungs from PAH patients. Secondary PAH lung samples were obtained from NDRI (n = 3). Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Original magnification, ×20 (A and B).
    Pasmcs Hmvecs, supplied by PromoCell, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pasmcs hmvecs/product/PromoCell
    Average 95 stars, based on 1 article reviews
    pasmcs hmvecs - by Bioz Stars, 2026-03
    95/100 stars
    		  Buy from Supplier

    Image Search Results


    Gremlin 1 expression in pulmonary arterial hypertension (PAH) clinical samples. A: Representative of high magnification images of colocalized expression of vWF and Grem1 in human pulmonary vessel endothelium. Arrows indicate positive staining. B: Lung sections from biopsies of controls and PAH patients were stained with an anti–Gremlin 1 antibody. Gremlin 1 staining in PAH patient is associated with plexiform lesions. Arrows indicate positive Gremlin 1 staining. C: Bone morphogenetic protein receptor type 2 (BMPR2) and Gremlin 1 mRNA analysis in primary microvascular endothelial cells (HMVEC) and pulmonary arterial smooth muscle cells (PASMCs). Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Data shown are representative from one donor of PASMCs and HMVECs. The experiments were performed in triplicate, with similar results observed in at least one other donor. D: Gremlin 1 mRNA expression in lungs from PAH patients. Secondary PAH lung samples were obtained from NDRI (n = 3). Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Original magnification, ×20 (A and B).

    Journal: The American Journal of Pathology

    Article Title: Treatment with Anti–Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416–Induced Pulmonary Arterial Hypertension in Mice

    doi: 10.1016/j.ajpath.2013.07.017

    Figure Lengend Snippet: Gremlin 1 expression in pulmonary arterial hypertension (PAH) clinical samples. A: Representative of high magnification images of colocalized expression of vWF and Grem1 in human pulmonary vessel endothelium. Arrows indicate positive staining. B: Lung sections from biopsies of controls and PAH patients were stained with an anti–Gremlin 1 antibody. Gremlin 1 staining in PAH patient is associated with plexiform lesions. Arrows indicate positive Gremlin 1 staining. C: Bone morphogenetic protein receptor type 2 (BMPR2) and Gremlin 1 mRNA analysis in primary microvascular endothelial cells (HMVEC) and pulmonary arterial smooth muscle cells (PASMCs). Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Data shown are representative from one donor of PASMCs and HMVECs. The experiments were performed in triplicate, with similar results observed in at least one other donor. D: Gremlin 1 mRNA expression in lungs from PAH patients. Secondary PAH lung samples were obtained from NDRI (n = 3). Quantitative changes in gene expression were analyzed by RT-PCR normalized to GAPDH (ΔΔCt method). Original magnification, ×20 (A and B).

    Article Snippet: Cell Culture of HMVECs and PASMCs HMVECs and PASMCs were obtained from Promocell; additional pulmonary arterial smooth muscle cells were purchased from Lonza.

    Techniques: Expressing, Staining, Reverse Transcription Polymerase Chain Reaction